Vacuum foam drying: An alternative to lyophilization for biomolecule preservation
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چکیده
منابع مشابه
Vacuum Foam Drying: An Alternative to Lyophilization for Biomolecule Preservation
Vacuum foam drying is evaluated as an alternative for lyophilization for enhanced process and storage stability of bovine serum albumin. The protein protective efficiency of different stabilizers was compared in vacuum foam drying and lyophilization. Sucrose mixtures produced better foam characters than mannitol. Unlike calcium lactate, incorporation of polyvinyl pyrrolidone to sucrose synergis...
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1 Department of Pharmaceutics, Seven Hills College of Pharmacy, Tirupathi, AP, India. 2 Faculty, Department of Pharmaceutics, OMER EL MUKHTAR University, Al-Beida, Libiya 3 Department of Pharmaceutical Chemistry, Shankarlingam Bhuvaneswari College of Pharmacy, Sivakasi, TN,India 4 Principal, Seven Hills College of Pharmacy, Tirupathi, AP, India 5 Research Director, Seven Hills College of Pharma...
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Water-washed Serratia marcescens (ATCC strain 14041) cells were lyophilized in an all-glass system capable of evacuation to pressures of less than 5 x 10(-6) torr. Lyophilization at the lowest pressures resulted in 50 to 65% survival for unstabilized washed organisms compared with 10 to 20% when the cells were lyophilized at pressures of about 2.5 x 10(-2) torr. At the latter pressures, 45 to 6...
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Since the pioneer work of Rogers (1914) on drying cultures from the frozen state and the wide application of this procedure to bacteria, the lyophil process has been shown to be a successful method for the preservation of yeast cultures in a viable state over extended periods (Elser et al., 1935; Wickerham and Andreasen, 1942; Wickerham and Flickinger, 1946). The fundamental value of this metho...
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ژورنال
عنوان ژورنال: Indian Journal of Pharmaceutical Sciences
سال: 2012
ISSN: 0250-474X
DOI: 10.4103/0250-474x.103837